Antimalarial compositions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514648, 514895, A61K 31335, A61K 31135

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active

056773315

ABSTRACT:
The invention relates to a synergistic antimalarial composition which comprises the antimalarial agent benflumetol and also an antimalarial agent from the artemisinine group such as artemether. The composition can be formulated into solid dosage forms such as tablets and is useful for the treatment of drug resistant malaria.

REFERENCES:
Deng, Chemical Abstracts, vol. 112, No. 7, Feb. 12, 1990 p. 1, Abstract No. 48094s.
Deng, Chinese Journal of Pharmaceuticals 1989, vol. 20, No. 8 pp. 372-376.
Who, "Practical Chemotherapy of Malaria", World Health Organization Technical Report Series 805 (1990).
Deng et al., Chemical Abstracts, vol. 114 p. 595 (1991), Abstract No. 6046p.
Wang et al., Chemical Abstracts, vol. 101, p. 385 (1984), Abstract No. 136941u.
CA 97(4): 28538h, Wang et al., 1982.
CA 113(5): 34389a, Sethi et al., 1988.
Merck Index, Therapeutic Catagory p. 16, 1989.
CA 103:134524, Lin et al., 1985.

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