Antigens and immunoassays for morphine and related 3-oxybenzomor

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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23230B, 260112R, 424 12, A61K 3900, G01N 3316, G21H 502

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active

040642283

ABSTRACT:
Antigens capable of generating antibodies specific to morphine and other 3-oxybenzomorphan compounds are prepared by conjugating 3-oxybenzomorphan derivatives with immunogenic carriers employing a linking site on an aryl group of the 3-oxybenzomorphan other than the hydroxyl substituent, so as to produce antibodies specific for the material.

REFERENCES:
patent: 3709868 (1973-01-01), Spector
patent: 3822245 (1974-07-01), Spector et al.
patent: 3843696 (1974-10-01), Wagner et al.
patent: 3884898 (1975-05-01), Schneider
Kabat, Structural Concepts in Immunology and Immunochemistry, Holt, Rinehart and Winston, Inc., New York, 1968, pp. 9-26.
Spector, Journal of Pharmacology and Experimental Therapeutics, vol. 178, No. 2, Aug., 1971, pp. 253-258.
Harwood, Pharmacology, vol. 11, 1974, pp. 52-57.

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