Antigenic protein originating in Malassezia

Details Antigenic protein originating in Malassezia Antigenic protein originating in Malassezia

2005-04-28

2009-02-17

Mondesi, Robert B (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Allergen or component thereof

C424S276100, C424S184100, C530S300000, C530S350000, C435S069100, C435S069700

Reexamination Certificate

active

07491405

ABSTRACT:
A substantially pure, isolated, antigenic protein from fungi of the genusMalassezia, characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergoses; an antigenic fragment derived from the antigenic protein; and an antibody against the antigenic protein or fragments thereof. According to the present invention, there can be provided an isolated and purified antigenic protein having high purity fromMalassezia, antigenic fragments thereof, and a specific antibody against those antigenic protein or fragments thereof. In addition, there can be provided a diagnostic agent, a therapeutic agent, or a prophylactic drug forMalasseziaallergoses, wherein the agent includes, as an active ingredient, the antigenic protein or fragments thereof.

REFERENCES:
patent: 6432407 (2002-08-01), Takesako et al.
Sentandreu et al., “Cloning of cDNA coding forCandida albicanscell . . . ”Journal of Medical&Veterinary Mycology, vol. 33, No. 2, 1995, pp. 105-111, XP001022554.
Lindblom et al., “Cloning and sequencing of the cDNA encoding thePityrosporum. . . ”Journal of Allergy and Clinical Immunology, vol. 97, No. 1 part 3, 1996, p. 374 XP001034009.
Yasueda et al., “Identification and cloning of two novel allergens from the lipophilic yeast . . . ”Biochemical and Biophysical Research Communications, vol. 248, No. 2, Jul. 20, 1998, pp. 240-244, XP002184076.
Moser et al., “Cloning and Expression of RecombinantAsperigilus”Journal of Immunology, vol. 149, No. 2, (1992) p. 454-460.
Johansson et al., “IgE-binding Components inPityrosporum orbiculare . . . ” Acta Derm Venereol(Stockh) vol. 71, 1991, pp. 11-16.
Zargari et al., “Identification of Allergen Components . . . ”,Allergy, 1994, vol. 49, pp. 50-56.
Jensen-Jarollim et al., “Atopic dermatitis of the face . . . ”,J. Allergy Clin. Immunolo., vol. 89, No. 1, 1992, pp. 44-51.
Arrunda et al., “Aspergillus fumigatusAllergenI . . . ”,J. Exp. Med., vol. 172, No. 5, 1990, pp. 1529-1532.
Garrard et al., “Two Genes Encode the Major Membrane . . . ”,J. Biol. Chem.vol. 264, No. 23, 1989, pp. 13929-13937.
Matsumoto et al., “Iron- and Manganese-Containing Superoxide . . . ”,Biochemistry, vol. 30, No. 13, 1991, pp. 3210-3216.
Ludwig et al., “Manganese Superoxide Dismutase . . . ”,J. Mol. Biol., vol. 219, No. 2, 1991, pp. 335-358.
Savolainen et al., “Crossreacting IgE Antibodies toPityrosporum . . . ”, Clinical and Experimental Allergy,vol. 22, 1992, pp. 469-474.
Rudinger et a., “Characteristics of the Amino Acids as Components . . . ”,Peptide Hormones, Edited by Parsons, University Park Press; Baltimore, 1976.
M. Carmen Menendez et al., “Cloning and expression ofMycobacterium fortuitumsuperoxide dismutase gene”, FEMS Microbiology Letters, vol. 134, No. 2-3, (1995), pp. 273-278. (XP-001063033.
R.A. Hallewell et al., “Sequence of a CDNA Coding For Mouse Manganese Superoxide Dismutase”, Nucleic Acids Research, vol. 14, No. 23, (Dec. 9, 1986), p. 9539. XP-001057377.

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