Antifungal and antiviral antibiotic, benanomicin A 4"'-O-sulfate

Details Antifungal and antiviral antibiotic, benanomicin A 4"'-O-sulfate Antifungal and antiviral antibiotic, benanomicin A 4"'-O-sulfate

1990-06-29

1992-02-25

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 64, 536 172, 536 179, 536 181, A61K 3170, C07H 1524

Patent

active

050913719

ABSTRACT:
As a new antifungal and antiviral antibiotic is provided benanomicin A 4"'-O-sulfate or a salt thereof having formula (I) ##STR1## wherein M.sup.1 denotes a mono-valent alkali metal atom or a di-valent alkaline earth metal atom or a hydrogen atom and A denotes an organic base; n is zero when M.sup.1 is an alkali metal atom or alkaline earth metal atom but n is 1 or zero when M.sup.1 is a hydrogen atom, and M.sup.2 denotes a hydrogen atom or an alkali metal atom or an alkaline earth metal atom. This new compound is useful as antifungal agent to treat fungal infections in mammals and as antiviral agent to inhibitingly treat HIV.

REFERENCES:
patent: 4393055 (1983-07-01), Nair et al.
patent: 4973673 (1990-11-01), Sawada et al.
The Merck Index, 9th ed., (1976) No. 7752, p. 1033.

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