Antibodies to stromal cell-derived factor-1 polypeptides

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387300, C530S388100, C530S388150

Reexamination Certificate

active

08058403

ABSTRACT:
Disclosed herein is a newly identified SDF-1 splice variant molecule, its polypeptide sequence, and the polynucleotides encoding the polypeptide sequence, and active fragments thereof. Also provided is a procedure for producing such polypeptides by recombinant techniques employing, for example, vectors and host cells. Also disclosed are methods for utilizing such polypeptides and modulators thereof for the treatment of diseases, including cancer, immune diseases, infectious diseases, and ischemic diseases.

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Nishimura et al., “Molecular Cloning and Sequencing of Feline Stromal Cell-derived Factor 1-α and β,”European Journal of Immunogenetics, 25(4): 303-305 (1998).
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U.S. Appl. No. 11/587,651, filed Jun. 30, 2008.

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