Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1991-11-04
1997-09-02
Scheiner, Toni R.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303871, 5303913, 5303911, 435 792, 435332, 435334, 436518, G01N 3353, C07K 1628
Patent
active
056633033
ABSTRACT:
The present invention discloses methods for preparing antibodies which bind to specific isoforms of the human retinoic acid receptor-.gamma. (RAR-.gamma.). In addition, several monoclonal antibodies are described which bind to human RAR-.gamma., but not to mouse or which bind to RAR-.gamma.1, but not to RAR-.gamma.2. Methods and kits are described which allow one to detect the isotype of RAR-.gamma. which is expressed in a test sample. Such methods are useful in determining the tissue specific pattern of expression of various RAR-.gamma. isoforms.
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Chambon Pierre
Gaub Marie-Pierre
Lutz Yves
Rochette-Egly Cecille
Saunders Michael
Centre National de la Recherche Scientifique
E.R. Squibb & Sons, Inc.
Institut National de la Sante et de la Recherche Medicale
Scheiner Toni R.
Universite Louis Pasteur, Strasbourg I
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