Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2005-05-25
2008-08-26
Helms, Larry R. (Department: 1643)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C435S326000, C435S069100
Reexamination Certificate
active
07417127
ABSTRACT:
The present invention belongs to the field of oncology. The invention relates to antibodies with specified sequence which are specific for an epitope which is coded by the variant exon v6 of the CD44 gene and to derivatives of said antibody. The invention also provides nucleic acid molecules encoding said antibody proteins. The invention furthermore pertains to methods for producing said antibody proteins. The invention also provides pharmaceutical compositions comprising said antibody proteins. The invention furthermore is concerned with the use in the manufacture of a medicament for the treatment of cancer.
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Adolf Gunther
Heider Karl-Heinz
Miglietta John J.
Ostermann Elinborg
Patzelt Erik
Boehringer Ingelheim Pharmaceuticals Inc.
Bohringer Ingelheim International GmbH
Helms Larry R.
Natarajan Meera
Sterne Kessler Goldstein & Fox P.L.L.C.
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