Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2007-01-23
2007-01-23
Siew, Jeffrey (Department: 1642)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387100, C530S501000, C435S007100
Reexamination Certificate
active
10721553
ABSTRACT:
A human nucleic acid, PD2, its encoded protein and antibodies immunologically specific thereto are disclosed herein. The expression of the disclosed PD2 gene plays a key role in the regulation of differentiation and in the maintenance of the neoplastic state. The PD2 gene and its encoded protein represent valuable therapeutic targets in the differential diagnosis and therapy of pancreatic adenocarcinomas.
REFERENCES:
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Results were produced by the gencore software version 4.5 1993-2000 p. 1-2.
Batra, S.K. et al., “Biology of Disease—Oncogenes and Anti-oncogenes in Human Central Nervous System Tumors”; Laboratory Investigation, 71(5): 621-637 (1994).
Batra, S.K. et al., “Isolation and Characterization of a Complementary DNA (PD-1) Differentially Expressed by Human Pancreatic Ductal Cell Tumors”; Cell Growth & Differentiation, 2: 385-390 (1991).
Griffin, C.A. et al. “Consistent Chromosome Abnormalities in Adenocarcinoma of the Pancreas”; Cancer Research, 55: 2394-2399 (1995).
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Batra Surinder K.
Hollingsworth Michael A.
Board of Regents of the University of Nebraska
Dann Dorfman Herrell and Skillman
Goddard Laura
Rigaut Kathleen D.
Siew Jeffrey
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