Antibiotic SF-1623 substance

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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195 80R, 424246, C07D50136, C12D 900

Patent

active

040101550

ABSTRACT:
A new antibiotic designated as SF-1623 substance exhibiting a useful antibacterial activity against gram-negative bacteria is now produced by cultivating a new strain ATCC 21999 of the known species Streptomyces chartreusis. The SF-1623 substance in the form of its an alkali metal salt may be recovered from the culture when the cultivation is effected under aerobic conditions in the presence of an alkali metal thiosulfate.

REFERENCES:
patent: 3219663 (1965-11-01), Demain
patent: 3278531 (1966-11-01), Cox et al.
patent: 3719563 (1973-05-01), Hamill et al.
Cama et al., J. Am. Chem. Soc, 94(4), pp. 1408-1410 (2/23/72).
Demain et al., Chemical Abstracts, vol. 58, 4763c (1963).
Nagarajan et al., J. Am. Chem. Soc., 93(9), 2308-2310, (1971).
Karady et al., J. Am. Chem. Soc., 94(4), 1410-1411, (1972).

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