Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1990-12-19
1994-04-26
Chan, Y. Christina
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 9, 530317, 530323, A61K 3702, C07K 754
Patent
active
053067088
ABSTRACT:
A new antibiotic cyclic lipopeptide having the formula ##STR1## wherein R is H SEQ ID NO:1 or OH SEQ ID NO:2 and a method of producing is described. The agent has very high activity against human pathogens and is of very low mammalian toxicity.
REFERENCES:
patent: 4737487 (1988-04-01), Watts et al.
patent: 5021341 (1991-06-01), Giacobbe et al.
Kurokawa et al., J. Am. Chem. Soc. 108: pp. 6041-6043 (1986).
Cram et al., Organic Chemistry, 2nd Edition, McGraw-Hill Book Company, New York pp. 607-613 (1964).
Hallada Thomas C.
Hensens Otto D.
Liesch Jerrold M.
Masurekar Prakash S.
Schwartz Robert E.
Chan Y. Christina
Merck & Co. , Inc.
Robertson Alice O.
Speer Raymond M.
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