Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-05-29
1992-02-04
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514375, 546270, 548221, A61K 3142, C07D26358
Patent
active
050860623
ABSTRACT:
This invention relates to certain benzoxazolinones which inhibit lipoxygenase and/or cyclooxygenase enzymes. Such compounds are useful in inhibiting such enzymes, per se, and are useful in treating allergic and inflammatory conditions in a mammal. This invention also relates to methods of inhibiting lipoxygenase and/or cyclooxygenase in a mammal with such benzoxazolinones; methods of treating an allergic condition in a mammal with such compounds; methods of treating an inflammatory condition in a mammal with such compounds; and pharmaceutical compositions comprising the benzoxazolinones hereof.
REFERENCES:
patent: 4835166 (1989-05-01), Kitaura et al.
The Scrip Leukotriene Report, 1985, PJB Publications Ltd., pp. i-iii and 1-25.
Ando Kazuo
Asai Nobuko
Ito Fumitaka
Mano Takashi
Nakane Masami
Benson Gregg C.
Daus Donald G.
Lumb J. Trevor
Pfizer Inc.
Richardson Peter C.
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