Anti-thrombotic peptide and pseudopeptide derivatives

Details Anti-thrombotic peptide and pseudopeptide derivatives Anti-thrombotic peptide and pseudopeptide derivatives

1990-04-05

1991-11-12

Doll, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 530331, A61K 3700, A61K 3702, C07K 500

Patent

active

050648144

ABSTRACT:
Disclosed are novel peptide and pseudopeptide derivatives and phrmaceutical compositions thereof that inhibit platelet aggregation and thrombus formation in mammalian blood.

REFERENCES:
patent: 3821188 (1979-06-01), McKinley et al.
patent: 4683291 (1987-07-01), Zimmerman et al.
Cheresh et al., "Biosynthetic & Func. Prop. of Arg-Gly Asp.", J. Biol. Chem., vol. 262, #36 12/25, pp. 17703-17711 (1967).
Fujimura, "Von Willebrand Factor", J. Biol Chem. v ol. 261 #1, 1/5 pp. 38-85 (1986).
Humphries et al., "Synthetic peptide from fibronectin", p. 467 Science, vol. 233 (1986).

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