Anti-platelet monoclonal antibody

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 71, 43524027, 53038822, 53038825, G01N 33574, G01N 3353, C12N 512, C07K 1528

Patent

active

053668650

ABSTRACT:
A method for producing novel monoclonal antibodies against purified platelets are provided. A monoclonal antibodies which inhibits platelet reactions with collagen or collagenous surfaces is described. A new method of detecting and treating tumor metastatis is described.

REFERENCES:
Giltay, J. C., Blood, 73(5):1235-1241, Apr. 1989.
Pischel, K. D., J. Clin Invest, 81:505-513, Feb. 1988.
Coller, et al., Clinical Research, 36(3):563A, 1988 (Abstract).
Staatz, et al., J. Cell. Biol. 108:1917-1924, May 1989.
McGregor et al., Eur. J. Biochem., 131:427-436, 1983.
Coller et al., Blood, 74(1):182-192, Jul. 1989.

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