Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1995-06-07
1999-02-09
Cunningham, Thomas M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
530351, 530300, 530317, 536 235, 514 2, A01K 3800, C07K 14705, C07H 2104
Patent
active
058690557
ABSTRACT:
The invention relates to anti-inflammatory polypeptides comprising soluble CD14 related polypeptides having amino acids at position 7-10 that are different from the native sequence or having amino acids 1-14 deleted.
REFERENCES:
Haziot et al. 1988 J. Immunology 141:547.
Ferrero et al. (1990) The Journal of Immunology 145:331-336.
Ferrero et al. (1988) Nucleic Acids Research 16:9.
Goyert et al. (1988) Science 239:497-500.
Juan et al. (1995) The Journal of Biological Chemistry 270: 1382-1387.
Pugin et al. (1994) Immunity 1:509-516.
Setoguchi et al. (1989) Biochimica et aBiophysia Acta1008:213-222.
Vinyakosol et al. (1995) The Journal of Biological Chemistry 270:331-368.
Juan et al. (1995), `Identification of a lipopolyaccharide binding domain in CD14 between amino acids 57 and 64`, J Bio Chem 270(10):5219-5224.
Juan et al. (1995), `Identification of a domain in sCD14 essential for Lipopolysaccharide (LPS) signaling but not LPS binding`, J. Bio Chem 207(29):17237-17242.
McGinley et al. (1995), `CD14: Physical properties and identification of an exposed site that is protected by Liopopolysaccharide`, J Bio Chem 270(10):5213-5218.
Weinstein (1983), `Chemistry and Biochemistry of Amino Acids, Peptides and Proteins`, Marcel Dekker, Inc. 7:336-345.
Juan Shao-Chieh
Lichenstein Henri S.
Wright Samuel D.
Amgen Inc.
Cunningham Thomas M.
Gaul Timothy J.
Levy Ron K.
Lubet Martha T.
LandOfFree
Anti-inflammatory CD14 polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-inflammatory CD14 polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-inflammatory CD14 polypeptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1946703