Anti-hypertensive derivatives of ergoline-2-thioethers and their

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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4242485, 424250, 424261, 544125, 544346, 544361, 546 67, 546 69, A61K 3155, A61K 3148, C07D45704, C07D45702

Patent

active

041972996

ABSTRACT:
A method for preparing ergoline derivatives in which the ergoline structure is variously substituted by morpholino-piperazino- and other active radicals to obtain novel compounds useful in cardiology as alpha-blocking, vasodilating, antihypertensive active ingredients of pharmaceutical preparations.

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Fusco-Bianchetti, Chimica Organica II, p. 584.
Kirk-Othmer, Encyclopedia of Chemical Technology, vol. 7, Interscience, New York, 1951, p. 840.
Kharasch, N., Organic Sulfur Compounds, vol. 1, Pergamon Press, New York, 1961, pp. 382-383.
Dryhurst, G., Periodate Oxidation of Diol and Other Functional Groups, , Pergamon Press, Oxford, 1966, pp. 61-64.

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