Anti-HIV oligomers

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active...

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525420, 525437, 525461, A61K 3174

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active

055715052

ABSTRACT:
The preferred oligomers of the present invention are polyureas, polycarbonates, polyesters or polyamides having a number average molecular weight of <10,000. These oligomers are water-soluble, have a rigid backbone, have recurring units coupled by carbonyl linking moieties which have anionic groups, display predominantly linear geomentry such that regular spacing between anionic groups exists in an aqueous medium, and are pharmaceutically-acceptable. The oligomers are useful for the treatment and/or diagnosis of AIDS and ARC.

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