Anti-EDA monoclonal antibody and a method for diagnosis of disea

Details Anti-EDA monoclonal antibody and a method for diagnosis of disea Anti-EDA monoclonal antibody and a method for diagnosis of disea

1993-09-22

1996-11-05

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

43524027, 53038825, G01N 3353, C12N 520, C07K 1618

Patent

active

055716792

ABSTRACT:
The invention provides an anti-EDA monoclonal antibody which recognizes an amino acid sequence portion in the EDA region of fibronectin (FN). The antibody of the invention has specific reactivity against EDA, in particular EDA-FN. By utilizing it, a simple and easy, high-sensitivity and high-precision immunoassay method for EDA-FN as well as a screening or diagnostic technique for EDA-FN-associated inflammatory and other diseases can be established.

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Clark et al. in "Enzyme Immunoassay", Maggio, E., Ed. pp. 167-179, 1989.

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