Anthracycline derivatives having cytostatic activity

Details Anthracycline derivatives having cytostatic activity Anthracycline derivatives having cytostatic activity

1987-12-04

1990-08-14

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 15252

Patent

active

049488805

ABSTRACT:
The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I, which are optionally in the form of a salt of an inorganic or organic acid, ##STR1## in which the substituents have the following meaning: R.sup.1 is hydrogen or a hydroxyl group,

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T. Oki, Microbial Transformation of Anthracycline Antibiotics and Development of New Anthracyclines, Anthracycline Antibiotics, 1982, pp. 75-96.
Essery et al., Can. J. Chem., vol. 58, 1980, pp. 1869-1874.

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