Animal cell culturing media containing N-acetyl-L-glutamic acid

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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435 41, 4352402, 4352403, 4351722, 530808, 530809, C12N 502, C12N 506, C12N 508, C12N 512

Patent

active

057190500

ABSTRACT:
The present invention relates to a medium composition for culturing animal cells which is obtained by combining at least one component selected from the group of substances mentioned below with a medium composition comprising inorganic salts, saccharides, vitamins and amino acids; a method for culturing animal cells comprising adding to a medium for the cells as a cell growth promoting substance at least one component selected from the group mentioned below; a method for enhancing the antibody production of antibody-producing cells comprising adding to a medium for the cells at least one component selected from the group mentioned below; a composition for enhancing the antibody production of antibody-producing cells which is obtained by combining at least one antibody production enhancing agent selected from the group mentioned below with a composition comprising inorganic salts, saccharides, vitamins and amino acids; and a method for producing a physiologically active substance comprising culturing animal cells on a medium containing at least one cell growth promoting substance selected from the group mentioned below, and then harvesting the cells grown or the substances produced by the cells.

REFERENCES:
patent: 4927762 (1990-05-01), Darfler
The Biochemical Journal, vol. 221, No. 1 (Jul. 1984) 255-60.
The Journal of Clinical Investigation, vol. 90, No. 4 (Oct. 1992) 1386-95.
Chemical Abstracts, vol. 90, No. 17 (1979) 133118z.
Journal of Cell Science, vol. 68 (1984) 285-303.
Federation Proceedings, vol. 43, No. 1 (Jan. 1984) 121-25.
Biotechnology & Bioengineering, vol. 32, No. 8 (Oct. 1988) 1015-1028.
Biotechnology Letters, vol. 9, No. 4 (1987) 259-64.

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