Angiotensin II type-1 receptor proteins and screening assays usi

Details Angiotensin II type-1 receptor proteins and screening assays usi Angiotensin II type-1 receptor proteins and screening assays usi

1995-04-05

1997-01-21

Fitzgerald, David L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 27, 435 691, 435 72, 530350, C07K 1472, G01N 33566, C12Q 102

Patent

active

055958826

ABSTRACT:
The present invention relates to (1) a human angiotensin II type 1 receptor protein, a recombinant DNA containing a gene which codes for said protein, a transformant carrying said DNA, production of said protein, and anti-angiotensin II substance screening methods using transformants containing said protein.

REFERENCES:
patent: 5427922 (1995-06-01), Fujisawa et al.
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Takayanagi et al., Biochem. Biophys. Res. Commun., 183(2), 910 (1992).
Murphy et al., Nature, 351, 233 (1991).
Sasaki et al., Nature, 351, 230 (1991).
Bergsma et al., "Cloning and Characterization of a Human Angiotensin II Type 1 Receptor", Biochem. Biophys. Res. Commun., 183(3), 989-995 (1992).
Kakar et al., "Angiotensin II Type-1 Receptor Subtype cDNAs: Differential Tissue Expression and Hormonal Regulation", Biochem. Biophys. Res. Commun., 183(3), 1090-1096 (1992).
Curnow et al., Mol. Endocrinol., 6, 1113-1118 (1992).
Sandberg et al., J. Biol. Chem., 267, 9455-9458 (1992).
Hahn et al., Biochem. Biophys. Res. Commun., 192(3), 1260-1265 (1993).

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