Chemistry of carbon compounds – Miscellaneous organic carbon compounds
Patent
1973-05-24
1976-07-13
Anderson, Harold D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
260 22R, 260 78A, 526 17, 526 42, C08F 800, C08F 832
Patent
active
039692841
ABSTRACT:
The application discloses polymers and methods of making same in which a chlorine atom of a chloromethyl pendant group of a polymer such as a chloromethylated copolymer of styrene and divinylbenzene is substituted with a derivative of malonic acid having a protected amino group on the alpha-carbon atom and two carboxyl groups or precursors thereof to form, via several steps, the alpha-amino acid derivative of the starting polymer. These polymers are used, for instance, as ion exchange resins, as substrates for affinity chromotography, and as a starting resin for solid peptide synthesis. The resultant polymer is also used as a starting material to make a polymer with a pendant group that is a derivative of oxazolidone-2,5-dione, substituted at the 4-position. These polymers are used, for example, as the matrix for solid phase peptide synthesis and as the starting resin for solid phase peptide degradation.
REFERENCES:
Journal of the American Chemical Society, vol. 67 (1945) pp. 502-503.
Flory- principles of Polymer Chemistry, 1953, pp. 75- 78, 102-103.
Anderson Harold D.
Heberling Richard D.
Owens--Illinois, Inc.
LandOfFree
Amino acid derivatives of chloromethylated polymers and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amino acid derivatives of chloromethylated polymers and methods , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amino acid derivatives of chloromethylated polymers and methods will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1738523