Amine-alkylborane derivatives and methods

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Boron containing doai

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564 9, 546 13, A61K 3169, C07F 502

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active

050235133

ABSTRACT:
Novel amine-alkylborane derivatives are disclosed which exhibit significant antineoplastic and antihyperlipidemic activities. Methods for preparing the compounds are disclosed as well as methods for utilizing the compounds to induce antineoplastic and antihyperlipidemic activity.

REFERENCES:
patent: 4312989 (1982-01-01), Spielvogel et al.
patent: 4368194 (1983-01-01), Spielvogel et al.
patent: 4587359 (1986-05-01), Spielvogel et al.
Publication by Spielvogel, et al., in the Journal of American Chemical Science, vol. 98, 1976, pp. 5702-5703.
Publication by Spielvogel, et al., in the Journal of American Chemical Science, vol. 102, 1980, pp. 6343-6344.
Publication by Spielvogel, et al., in Inorganic Chemistry, vol. 23, 1976, pp. 1776-1777.
Publication by Spielvogel, et al., in Inorganic Chemistry, vol. 23, 1984, pp. 4233-4324.
Publication by Spielvogel, et al., in the Journal of Pharmaceutical Sciences, vol. 70, No. 3, Mar. 1981, pp. 339-341.
Publication by Spielvogel, et al., in the Journal of Pharmaceutical Sciences, vol. 76, No. 5, May 1987, pp. 359-365.

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