Amidine derivatives with nitric oxide synthetase activities

Details Amidine derivatives with nitric oxide synthetase activities Amidine derivatives with nitric oxide synthetase activities

1998-07-08

2000-02-29

Jarvis, William R. A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514326, 514427, 514438, 514637, A61K 3147, A61K 31445, A61K 3140, A61K 3138, A61K 31155

Patent

active

060309857

ABSTRACT:
The present invention relates to methods and compositions useful for treating and preventing conditions in which inhibition of nitric oxide synthetase is beneficial. These conditions include stroke, schizophrenia, anxiety, and pain.

REFERENCES:
patent: 3299081 (1967-01-01), Sletzinger et al.
patent: 3669974 (1972-06-01), Elpern et al.
patent: 5266594 (1993-11-01), Dawson et al.
Moncada et al, "Nitric oxide; Physiology, . . . " Pharmacological Reviews, vol. 43, pp. 109-142 (1991).
Nissan Chem. Ind. KK (1989) "Fluorine-contg cpds." (0-38310/42).
Forstermann et al, "Induced RAW 264.7 macrophages express," European J. of Pharmacology-Molec. Pharmac. Sect. vol. 225, pp. 161-165 (1992).
Bredt et al, "Isolation of nitric oxide synthetase . . . ," Proc. Natl. Acad. Sci. (USA), vol. 87, pp. 682-685 (1990).
Pollock et al, "Purification and characterization of . . . ," Proc. Natl. Acad. Sci. (USA), vol. 88, pp. 10480-10484 (1991).

Affiliated with

Also associated with

Rating

Amidine derivatives with nitric oxide synthetase activities does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amidine derivatives with nitric oxide synthetase activities, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amidine derivatives with nitric oxide synthetase activities will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-683362