Amidase from variovorax

Details Amidase from variovorax Amidase from variovorax

2006-07-04

2006-07-04

Patterson, Jr., Charles L. (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S135000, C435S228000

Reexamination Certificate

active

07070963

ABSTRACT:
The present invention relates to an amidase enzyme, nucleic acids encoding the amidase, as well as methods of employing the nucleic acids and/or amidase to produce, for example, enantiomericallyenriched compounds such as D-amino acids.

REFERENCES:
patent: 0 334 358 (1989-09-01), None
patent: WO 97/12964 (1997-01-01), None
Krieg, L, et al. (2002) Adv. Synth. Catal. 344(9), 965-973.
T. Hayashi, et al., Journal of Fermentation and Bioengineering, vol. 83, No. 2, pp. 139-145, XP-009009228, “Characterization and Cloning of an Enantioselective Amidase FromComamonas acidovoransKPO-2771-4”, 1997 (with corr. Database EMBL ‘Online!’, AN AAT47765,).
Database EMBL ‘Online’, AN AAT47765, pp. 1-2, XP-002237979, “Comamonas acidovoransDerived Amidase Gene”, May 2, 1997.
A. Ozaki et al., Bioscience Biotechnology and Biochemistry, vol. 57, No. 3, pp. 520-521, XP-009009243, “A D-Amidase Constitutive Mutant FromArthrobactersp. NJ-26”, 1993.
J. R. Leadbetter, et al., Journal of Bacteriology, vol. 182, No. 24, pp. 6921-6926, XP-002208346, “Metabolism of Acy1-Homoserine Lactone Quorum-Sensing Signals byVariovorax paradoxus”,Dec. 2000.

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