Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Reexamination Certificate
2007-05-22
2007-05-22
Huff, Sheela J. (Department: 1643)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
C424S009100, C424S009300, C424S009340, C424S009400
Reexamination Certificate
active
10300531
ABSTRACT:
The invention provides diagnostic procedures wherein the presence or absence of a cell-proliferating disorder, e.g., a breast cancer, may be determined. The imaging agents of the invention include alpha-fetoprotein hydrophilic analogs which have been determined to target cancers, e.g., breast cancer, and are also anti-cell proliferating in nature. These modulators contain amino acid structures which are arranged as a hydrophilic analog of an alpha-fetoprotein. The modulator may be a peptide; a peptidomimetic; or may be in the form of a pharmaceutically acceptable scaffold, such as a polycyclic hydrocarbon to which is attached the necessary amino acid structures. The imaging agents of the invention further comprise an imaging moiety that allows for the imaging of the area targeted by the imaging agent.
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Andersen Thomas T.
Bennett James A.
Jacobson Herbert I.
Mesfin Fassil B.
Biswas, Esq. Naomi S.
Elrifi, Esq. Ivor R.
Huff Sheela J.
Mintz Levin
Ordway Research Institute, Inc.
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