Alkylenediamine derivatives

Details Alkylenediamine derivatives Alkylenediamine derivatives

1991-08-07

1994-05-10

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540604, 540609, 540610, 546215, 546218, 546222, 546229, 546232, 548530, 548532, 548536, 548538, 548540, 548543, 548550, 548569, C07D22300, C07D21126

Patent

active

053109023

ABSTRACT:
Novel alkylenediamine derivatives effectively employable glutamate blockers have the formula (I) or (II): ##STR1## wherein each of R.sup.1 and R.sup.6 is an aliphatic hydrocarbon group, an alicyclic hydrocarbon group, an aryl group, or an aralkyl group; each of R.sup.2 and R.sup.7 is an aliphatic hydrocarbon group, an alkoxy group, an aliphatic hydrocarbon group containing an ester bonding, an aliphatic hydrocarbon group containing an ether bonding, or an aryloxy group; each of R.sup.3, R.sup.4, R.sup.5 R.sup.8, R.sup.9 and R.sup.10 is hydrogen, an alkyl group, an alkoxy group, an acyloxy group, an aryl group, an aralkyl group, hydroxyl, a hydroxylalkyl group, halogen, nitrile, nitro, amino, carbamoyl or alkoxycarbonyl; and each of m and n is an integer of 0-3 (m+n does not exceed 3); k is an integer of 1-4; each of p and i is an integer of 2-13; and each of q and j is an integer of 4-7.

REFERENCES:
patent: 4364954 (1982-12-01), Pattison
patent: 4906634 (1990-03-01), Greenberg et al.
patent: 5059391 (1991-10-01), Botta et al.

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