Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-07-10
1990-04-10
Springer, David B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548253, C07D40908
Patent
active
049162314
ABSTRACT:
Tetrazole derivatives represented by the formula: ##STR1## wherein R is naphthyl or phenyl optionally substituted by phenyl, lower alkyo, halogen, lower alkoxy, hydroxy or acetoxy; X is methylene, dimethylmethylene or oxygen; n is an integer of 0 or 1; and p and r each is an integer of 0 or 1 and q is an integer of 1 or 2 provided that p+q+r=2; or a tautomer in tetrazole ring and a pharmaceutically acceptable salt thereof, which are useful as TXA.sub.2 receptor antagonist.
REFERENCES:
patent: 4670453 (1987-06-01), Das
patent: 4749715 (1988-06-01), Hall
Hagishita Sanji
Matsuura Takaharu
Narisada Masayuki
Ohtani Mitsuaki
Seno Kaoru
Shionogi & Co. Ltd.
Springer David B.
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