(Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls use

Details (Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls use (Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls use

1995-06-01

1997-02-11

Higel, Floyd D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514365, 514381, 514397, 514398, 514399, 544 3, 548181, 548252, 548254, 5483061, 5483064, A61K 3154, C07D27902

Patent

active

056021275

ABSTRACT:
Angiotensin-II antagonists of the formula ##STR1## wherein R.sub.1 is, other than hydrogen and, inter alia, halogen, lower alkyl or cycloalkyl; R.sub.2 is, inter alia, optionally substituted benzimidazol-2-yl, 5,6,7,8-tetrahydro-imidazo [1,2-a]pyridin-2-yl, butanesultam-1-yl, imidazol-4-yl, and tetrahydobenzimidazol-2-yl; R.sub.3 is, inter alia, lower alkyl; and, R.sub.4 is an acidic group, such as carboxyl or tetrazolyl. An exemplary compound is: 4'-[(2-n-propyl-4-methyl-6-(butanesultam-1-yl)benzimidazol-1-yl)-methyl]-b iphenyl-2-carboxylic acid.

REFERENCES:
patent: 3929814 (1975-12-01), Narayanan et al.
patent: 4492708 (1985-01-01), Spitzer
patent: 5171748 (1992-12-01), Roberts et al.
patent: 5189048 (1993-02-01), Carini et al.
patent: 5190942 (1993-03-01), Poss
patent: 5194435 (1993-03-01), Kees
patent: 5200422 (1993-04-01), Olesen et al.
patent: 5218125 (1993-06-01), Chen et al.
patent: 5250554 (1993-10-01), Naka et al.
patent: 5254546 (1993-10-01), Ardecky et al.

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