Agent for inhibiting proliferation of neural stem cells

Details Agent for inhibiting proliferation of neural stem cells Agent for inhibiting proliferation of neural stem cells

2007-02-09

2010-02-16

Ulm, John D. (Department: 1649)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds hormone or other secreted growth regulatory factor,...

C435S368000, C435S377000, C424S130100, C530S387100

Reexamination Certificate

active

07662385

ABSTRACT:
The object of the present invention is to provide methods for inhibiting proliferation of neural stem cells, an agent for inhibiting proliferation of neural stem cells, and methods for using the same. According to the method of the present invention, a galectin-1 inhibitor such as anti-galectin-1 antibody and/or an integrin β1 inhibitor such as anti-integrin β1 antibody is administered to a human or a vertebrate other than human for inhibiting proliferation of neural stem cells. This method can be used for treatment of nerve injury and nerve tumors.

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