Aerothricin derivatives

Details Aerothricin derivatives Aerothricin derivatives

2005-02-01

2005-02-01

Wax, Robert A. (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

C530S321000, C530S323000, C530S332000, C514S011400, C514S014800, C514S009100, C435S071100, C435S254100, C435S911000

Reexamination Certificate

active

06849709

ABSTRACT:
The present invention relates to novel Aerothricins represented by the Formula (I),and pharmaceutically acceptable salts thereof.The present invention also relates to a pharmaceutical composition comprising an Aerothricin of the Formula (I) and a pharmaceutically acceptable carrier. Furthermore, the present invention relates to the use of such Aerothricins for the preparation of medicaments, as well as to processes for the preparation of the Aerothricins of the Formula (I).

REFERENCES:
patent: 5547934 (1996-08-01), Fujie et al.
patent: 6489440 (2002-12-01), Aoki et al.
patent: 20010038824 (2001-11-01), Horii et al.
patent: 584 360 (1994-03-01), None
patent: 736 541 (1996-10-01), None
patent: 9630399 (1996-10-01), None
patent: 0005251 (2000-02-01), None
David Barrett et al., Fujisawa Pharmaceuticals, “Synthesis and Biological Activity of Novel 1,3-beta-Glucan Synthase Inhibitors Derived from FR 9014690, an Antifungal Antibiotic”, 19thSymposium of Medicinal Chemistry, 8thAnnual Meeting of Division of Medicinal Chemistry Abstract 2P-14, p. 123 (1999).

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