Adhesive tape preparation of clonidine

Stock material or miscellaneous articles – Web or sheet containing structurally defined element or... – Adhesive outermost layer

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428422, 428343, 424448, 424449, 602 52, B32B 712, A61F 1300, A61L 1516, A61K 970

Patent

active

051750520

ABSTRACT:
An adhesive tape preparation of clonidine is disclosed, comprising a polytetrafluoroethylene porous sheet having an air permeability of from 10 to 500 seconds having thereon an active ingredient-containing layer comprising a pressure-sensitive adhesive obtained by copolymerizing a monomer mixture comprising from 40 to 80% by weight of 2-ethylhexyl acrylate, from 20 to 60% by weight of 2-methoxyethyl acrylate, and 0 to 40% by weight of vinyl acetate, the pressure-sensitive adhesive containing clonidine as an active ingredient. The preparation achieves sustained release of clonidine and exhibits long-term preservability while minimizing skin irritation and maintaining sufficient adhesion to the skin.

REFERENCES:
patent: 4346709 (1982-08-01), Schmitt
patent: 4592753 (1986-06-01), Panoz
patent: 4608249 (1986-08-01), Otsuka et al.
patent: 4765974 (1988-08-01), Tokuda et al.
patent: 4822617 (1989-04-01), Panoz
patent: 4994278 (1991-02-01), Sablotsky et al.
WPIL, File Supplier, AN.dbd.90-0040-27 (01), Derwent Publications Ltd., London, GB; & JPA 01 287 024.
Patent Abstracts of Japan, vol. 12, No. 306 (C-522)[3153], Aug. 19, 1988.

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