Adhesion receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514212, 514255, 514364, 514374, 540603, 544369, 546208, 548134, 548135, 548230, A61K 31445, A61K 3142, C07D26324, C07D41312

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active

056145357

ABSTRACT:
Compounds of the formula I ##STR1## in which R.sup.1 and X have the meanings herein defined, their physiologically unobjectionable salts and/or solvates inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporosis, tumoral diseases, apoplexy, cardiac infarction, inflammations, arteriosclerosis and osteolytic disorders.

REFERENCES:
patent: 2437388 (1948-03-01), Homeyer et al.
patent: 4866182 (1989-09-01), Schnettler et al.
patent: 5356918 (1994-10-01), Ishihara et al.
Vajta et al. "Reversed-phase high performance liquid chromatographic separation of 14C-labeled toloxatone and tis metabolites" CA 102:5518 1984.
Born, Nature, 4832:927-929 (1962).
Smith et al., J. Biol. Chem., 265:12267-12271 (1990).

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