Acylated oligopeptides for transfecting cells

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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4351723, 435244, 514 2, 935 33, 935 34, 935 52, 935 54, C12N 1500

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057598274

ABSTRACT:
Compounds of the formula

REFERENCES:
Helv. Chim. Acta, pp. 526-543, (See pp. 543-544 for English language summary) (1964).
Felgner, et al, Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure, Proc. Natl. Acad. Sci, vol. 84, pp. 7413-7417 (1987).
Behr, Gene Transfer with Synthetic Cationic Amphiphiles: Prospects for Gene Therapy, Bioconjugate Chem., vol. 5, pp. 382-389 (1994).
Gao, et al, Cationic liposome-mediated gene transfer, Gene Therapy. vol. 2, pp. 710-722 (1995).
Kabanov, et al. DNA Complexes with Polycations for the Delivery of Genetic Material into Cells, Bioconjugate Chem., vol. 6, pp. 7-20 (1995).
Ledley, Nonviral Gene Therapy: The Promise of Genes as Pharmaceutical Products, Human Gene Therapy, vol. 6, pp. 1129-1144 (1995).
Kabanov et al. "DNA Complexes with Polycations for the Delivery of Genetic Material into Cells", Bioconjugate Chemistry, vol. 6, No. 1(1995), pp. 7-20. QP517.B49B56.
Lee et al. "Folate-Targeted, Anionic Liposome-Entrapped Polylysine-Condensed DNA for Tumor Cell-Specific Gene Transfer", Journal of Biological Chemistry, vol. 271, No. 14 (Apr. 5, 1996), pp. 8481-8487. QP501.J7.
Volger et al. "Ferrsaurehaltige basiche Peptide mit Antibakterieller Wirkung", Helvetica Chimic Acta, vol. 47 (1964), pp. 526-543. QD1.H4.

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