Acyclic nucleoside phosphonate derivatives, salts thereof...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

Reexamination Certificate

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C544S118000, C544S244000, C544S243000, C558S189000

Reexamination Certificate

active

10450780

ABSTRACT:
The present invention relates to a nucleoside phosphonate derivative represented by formula (1):pharmaceutically acceptable salts, and stereoisomers. This nucleoside phosphonate derivative is useful as an antiviral agent, particularly, against hepatitis B virus. Also disclosed are processes for the preparation of the nucleoside phosphonate derivative. Also disclosed are methods treating hepatitis B by administering a nucleoside phosphonate derivative of formula (1).

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