Activation of recombinant proteins

Details Activation of recombinant proteins Activation of recombinant proteins

1993-10-21

1996-11-26

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Separation or purification

435 691, 435 695, 435 6951, 435 6952, 530351, A23J 100, C07K 100, C12P 2106

Patent

active

055787100

ABSTRACT:
A process for the activation of recombinant proteins which are present in at least a partially inactive form in which a protein is activated by known solubilization or/and renaturation techniques, said protein having additional helper sequences 2 to 50 amino acids in length at its N- or/and C-terminus whereby the relative hydrophobicity of these helper sequences which is calculated as the sum of the relative hydrophobicity specified in Table 1 for the individual amino acids has a negative numerical value.

REFERENCES:
patent: 4530787 (1985-07-01), Shaked et al.
patent: 4783415 (1988-11-01), Hoshiko et al.
patent: 4948729 (1990-08-01), Piatak, Jr. et al.
patent: 5013653 (1991-05-01), Huston et al.
patent: 5043156 (1991-08-01), Matsumoto et al.
patent: 5077392 (1991-12-01), Rudolph et al.
patent: 5082775 (1992-01-01), McCaman et al.
patent: 5087564 (1992-02-01), Mai et al.
patent: 5115102 (1992-05-01), Haymore et al.
patent: 5191063 (1993-03-01), Inouye et al.
Mulks et al. "Relationship Between the Specificity of IgA Proteases and Serotypes in Haemophilus influenzae", Journal of Infectious Diseases, vol. 146, No. 2, Aug. 1982, pp. 265-274.
Mulks et al. (1980) Jour. Exp. Med. vol. 152 pp. 1442-1447.

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