Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1991-07-31
1993-12-14
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514456, 514520, 514619, 514622, 514866, 549398, 549404, 549407, 558404, 558413, 564166, 564167, 564172, 564174, 564175, 564181, 564183, A61K 31165, C07C23305
Patent
active
052703428
ABSTRACT:
The invention concerns novel N-phenylacetyl and related acyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives.
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Brittain David R.
Brown Steven P.
Cooper Anthony L.
Longridge Jethro L.
Morris Jeffrey J.
Hollrah Glennon H.
Imperial Chemical Industries plc
Kumar Shailendra
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