Acetal derivatives of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodia

Details Acetal derivatives of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodia Acetal derivatives of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodia

1973-10-12

1976-03-23

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239BD, 2602393D, 260338, 2603407, 2603409, 260535R, 260561H, 424269, C07D48704

Patent

active

039460320

ABSTRACT:
Compounds of the class of acetals of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-carboxaldehyde and the 5-oxides and pharmaceutically acceptable acid addition salts thereof have valuable pharmacological properties, in particular anticonvulsant effectiveness. Further, they show central depressant and muscle-relaxing activity and are active ingredients for therapeutic preparations. Specific embodiments are 6-phenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-carboxaldehyde -diethylacetal, 6-(o-chlorophenyl)-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-carb oxaldehyde-diethylacetal and 6-(o-fluorophenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-carbo xaldehyde-diethylacetal.

REFERENCES:
patent: 3681343 (1972-08-01), Hester

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