ABCA-1 elevating compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S266200, C514S365000, C514S367000, C514S406000

Reexamination Certificate

active

06900219

ABSTRACT:
The present invention provides compounds that elevate cellular expression of the ABCA-1 gene, promoting cholesterol efflux from cells and increasing HDL levels in the plasma of a mammal, in particular humans. The compounds are useful for treating coronary artery disease.

REFERENCES:
patent: 6548548 (2003-04-01), Campbell et al.
patent: 2002/0082257 (2002-06-01), Ibrahim et al.
patent: 2002/0128266 (2002-09-01), Campbell et al.
patent: 2003/0069234 (2003-04-01), Medina et al.
patent: WO 01/16114 (2001-03-01), None
patent: WO 02/083143 (2002-10-01), None
patent: WO 01/81346 (2002-11-01), None

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