A83543 compounds and process for production thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424DIG8, 424DIG10, 536 41, 536 168, 536 71, 536 75, A61K 3171, C07H 1704, C12P 1962

Patent

active

056704860

ABSTRACT:
New A83543 components, including fermentation products A83543K, A83543O, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.

REFERENCES:
patent: 2881162 (1959-04-01), Walasek
patent: 3725385 (1973-04-01), Freiberg
patent: 4148883 (1979-04-01), Celmer et al.
patent: 4206206 (1980-06-01), Mori et al.
patent: 4213966 (1980-07-01), Liu et al.
patent: 4224314 (1980-09-01), Celmer et al.
patent: 4251506 (1981-02-01), Laby
patent: 4251511 (1981-02-01), Whaley et al.
patent: 4273920 (1981-06-01), Nevin
patent: 4293651 (1981-10-01), Whaley et al.
patent: 4321329 (1982-03-01), Whaley et al.
patent: 4366308 (1982-12-01), Soma et al.
patent: 4421760 (1983-12-01), Box
patent: 4448970 (1984-05-01), Magerlein
patent: 4482707 (1984-11-01), Sakakibara et al.
patent: 4501752 (1985-02-01), Yokoi et al.
patent: 4508647 (1985-04-01), Hatori et al.
patent: 4514562 (1985-04-01), Toscaro
patent: 4515942 (1985-05-01), Iwasaki et al.
patent: 4530835 (1985-07-01), Bunge et al.
patent: 4560509 (1985-12-01), Johnson et al.
patent: 4568740 (1986-02-01), Oppici et al.
patent: 4764602 (1988-08-01), Kumagai et al.
patent: 4831016 (1989-05-01), Mrozik et al.
patent: 5003056 (1991-03-01), Nishikiori et al.
patent: 5028536 (1991-07-01), Golik et al.
patent: 5202242 (1993-04-01), Mynderse et al.
patent: 5227295 (1993-07-01), Baker et al.
patent: 5362634 (1994-11-01), Boeck et al.
Whaley et al., Tetrahedron Letters (1980), 21:3659.
Snyder et al., J. Am. Chem. Soc. (1984), 106:787.
Celmer et al., J. Chem. Soc., (1980) 102:4203.
Ikeda et al., (1985) J. Antibiotic, 38:436.
Umezawa (1980),Supplement to Index of Antibiotics from Actinomycetes, Journal of Antibiotics, 33(3):15-26.
Umezawa, Institute of Microbial Chemistry, Tokyo, Index of Antibiotics from Actinomycetes, vol. II (1967).
Sakano et al.(1980), J. Antibiot. (Tokyo), 33(7):683-689.
Brown et al. (1986), J. Liq. Chromatography, 9(4):831-844.
Chen et al. (1981), ACTA Microbiol. Sin., 21(2):192-196 (Biosis abstract).
Drioli, (1986), Separation, Recovery and Purification in Biotechnology, 52-66.
Kubo et al. (1985), Analytical Letters, 18(B3):245-260.
Brode et al. (1986), Arzneim-Forsch, 36(3):437-442.
Julien et al. (1988), Clin. Chem., 34(5):966-969.
Chemical Abstracts, vol. 87, No. 24, issued Dec. 1977, R. Datta et al., "Concentration of antibiotics by reverse osmosis," see p. 310, see the abstract No. 189423a, Biotechnol. Bioeng. 1977, vol. 19, No. 10, pp. 1419-1429.
Cram et al. (1964), Organic Chemistry, 2nd Ed., p. 204.
Journal of American Chemical Society, (1992), vol. 114, No. 6, pp. 2260-2262 Evans, et al. "Asymmetric Synthesis of the Macrolide (+)-A83543A (Lepicidin) Aglycone," see the whole document.
Chemical Abstracts (1991), vol. 114, No. 80066m, Boeck et al.
Biosis Abstract 90:127301 Mertz et al., "Int. J. Syst. Bact." 40(1) 1990 34-39.
ACS Symposium Series, Synthesis and Chemistry of Agrochemicals III, vol. 504, 1992, pp. 214-225, Kirst, et al., "Discovery, Isolation, and Structure Elucidation of a Family of Structurally Unique, Fermentation-Derived Tetracyclic Macrolides", See abstract. See p. 216, paragraph 2; p. 217, paragraph 1.
Jacobson, G.K., "Mutations" Chapter 5b of Biotechnology vol. 1, H.-J. Rehm and G. Reed, eds. (1981).
Journal of the Chemical Society, (1964), London, GB; Birch et al.: "Studies in Relation to Biosynthesis. Part XXXV. Macrolide Antibiotics to Biosynthesis. Part XII. Methymycin", pp. 5274-5278.
Chemical Abstracts, (1979), vol. 90, No. 19, p. 591, col. 2--p. 592, col. 1, abstract No. 151957b, Columbus, Ohio; Inanaga et al.: "Synthesis of Methynolide", & Tennen Yuki Kagobutsu Toronkal Koen Yoshishu, 21st 1978, 324-30 (abstract).
Kirst et al., Tetrahedron Letters (1991), 32(37):4839-4842.
Omura and Tannaka (1984), Macrolide Antibiotics, Chapter 1.
Schulman and Ruby (1987), Antimicrobial Agents and Chemotherapy, 31(6):964-965.
Ito and Hirata (1972), Tetrahedron Letters, 12:1185-1188.
Aizawa et al., (1979), The Journal of Antibiotics, 32(3):193-196.
Jomon et al., (1972), The Journal of Antibiotics, 25(5):271-280.
Dybas and Babu (1988), Brighton Crop Protection Conference, 57-64.
Borchardt et al. (1979), Biochem. & Biophys. Res. Comm., 89(3):919-924.
Vedel et al., (1978), Biochem. & Biophys. Res. Comm.,85(1):371-376.
Pickett, J.A., (1988), Chemistry in Brittain, 137-142.
Omura, (1984), Macrolide Antibiotics, Chapter 13.
Fuller (1978), Biochemical Pharmacology, 27:1981-1983.
Jackson et al. (1988), Abstracts of the 1988 ICAAC, 26026.
Derwent Abstract 84-278337/45,SSSE Mar. 16, 1983.
Derwent Abstract 84-252941/41, SSSE Feb. 16, 1983.
Derwent Abstract 92: 144960k.
Derwent Abstract 11667c/07, KAKE May 31, 1978.
Derwent Abstract 92:211459u.
Derwent Abstract 88-095030/14, SSSE 00.00.86.
Derwent Abstract 85-245719/40, SSSE Feb. 1, 1984.
Derwent Abstract 54333S-BCD,Fuji, Feb. 17, 1969.
Catalogue of Bacteria and phages, ATCC, 7th Ed., 1989.
Kreuzman et al., J. Biological Chemistry (1988), 263 (30): 15626-15633.
Schulman et al., Journal of Antibiotics 38(11): 1494-98 (1985).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

A83543 compounds and process for production thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with A83543 compounds and process for production thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A83543 compounds and process for production thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1938673

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.