8-Chloro-5,6,7,8-tetrahydro-2-quinolone and 8-bromo-5,6,7,8-tetr

Details 8-Chloro-5,6,7,8-tetrahydro-2-quinolone and 8-bromo-5,6,7,8-tetr 8-Chloro-5,6,7,8-tetrahydro-2-quinolone and 8-bromo-5,6,7,8-tetr

1979-09-13

1980-10-07

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260155, C07D21522

Patent

active

042269970

ABSTRACT:
8-Chloro-5,6,7,8-tetrahydro-2-quinolone and 8-bromo-5,6,7,8-tetrahydro-2-quinolone, the hydrochloride or hydrobromide thereof and their manufacture by reacting 3,4,5,6,7,8-hexahydro-2-quinolone with chlorine or bromine in an inert solvent at 10.degree. to 50.degree. C. with heating of the reaction mixture to 60.degree. to 80.degree. C. after the halogen addition.

REFERENCES:
patent: 3853896 (1974-12-01), Pessolano et al.
patent: 4006237 (1977-01-01), Buckle et al.
patent: 4071520 (1978-01-01), Wehrmeister
Elderfield, Heterocyclic Compounds, vol. 4, pp. 129-137 (1952).

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