8-Aminoalkylpsoralens

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic or structurally-modified peptidoglycan or...

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Details

424 59, 548463, 549282, C07D49304, A61K 31365

Patent

active

043282393

ABSTRACT:
The invention relates to 8-aminoalkylpsoralens, having essentially no erythematic photosensitizing activity but at the same time having substantial DNA-binding photosensitizing activity, making them of especial interest from the standpoint of suntanning and psoriasis treatment, characteristics which are unpredictable when the compounds are compared with psoralens of similar but different structure.

REFERENCES:
patent: 4124598 (1978-11-01), Hearst et al.
patent: 4169204 (1979-09-01), Hearst et al.
patent: 4269851 (1981-05-01), Kaufman
Hearst et al. (II), Chem. Abst. 87:78962f, 1977.
Issacs et al., Chem. Abst. 86:135108n.
Johnston et al., Chem. Abst. 87:147284a.
Shen et al., Chem. Abst. 88:59494j.

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