8-(1H-Tetrazol-5-yl)-11H-pyrido[2,1-b]quinazolin-11-ones and met

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260251A, 2602564F, A61K 31505, C07D47104

Patent

active

040667677

ABSTRACT:
The present invention relates to 8-(1H-tetrazol-5-yl)-11H-pyrido[2,1-b]quinazolin-11-ones having the following structure: ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen, alkyl, alkyloxy, halogen, hydroxy and methylenedioxy; R.sub.3 is carboxamido, cyano or 5-tetrazolyl groupings and the pharmaceutically acceptable salts of acids and bases thereof.
These compounds exhibit anti-allergic properties and are useful as anti-asthmatic agents.

REFERENCES:
patent: 3966965 (1976-06-01), Sellstedt et al.
patent: 3982000 (1976-09-01), Hardtmann
patent: 4012387 (1977-03-01), Schwender et al.
patent: 4033961 (1977-07-01), Schwender et al.
Laboratories U.P.S.A., Chemical Abstracts, 64, 712h-713d (1966).

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