7-(n-substituted amino)-2-phenylheptanoic acid derivative and pr

Details 7-(n-substituted amino)-2-phenylheptanoic acid derivative and pr 7-(n-substituted amino)-2-phenylheptanoic acid derivative and pr

1997-07-16

1998-09-01

Kumar, Shailendra

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 12, 560 31, 560 37, 560 38, 560 39, 554 36, 5483361, 5483381, C07C27106, C07C26906

Patent

active

058012710

ABSTRACT:
Disclosed is a 7-(N-substituted amino)-3-oxo-2-phenylheptanoate derivative, 7-(N-substituted amino)-3-hydroxy-2-phenylheptanoate derivative, and 7-(N-substituted amino)-3-benzenesulfonyloxy-2-phenylheptanoate derivative, which are quite important major intermediates for an antidepressant. The 7-(N-substituted amino)-3-oxo-2-phenylheptanoate derivative can be manufactured by condensing an enolate of phenylacetates with a 5-(N-substituted amino) pentanoate derivative.

REFERENCES:
patent: 3406165 (1968-10-01), Kruckenberg
patent: 3467690 (1969-09-01), Chamberlin
patent: 5371271 (1994-12-01), Kruger et al.

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