7 -[D.alpha.-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-.alpha.

Details 7 -[D.alpha.-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-.alpha. 7 -[D.alpha.-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-.alpha.

1980-02-14

1981-09-08

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, C07D50140

Patent

active

042885906

ABSTRACT:
7-[D-.alpha.-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-.alpha.-phenyl (and thienyl and substituted phenyl) acetamido]-3-(2-, 3- or 4-N,N-dimethylaminomethyl-pyridinium)methyl-3-cephem-4-carboxylates were synthesized and found to have potent antibacterial activity in vitro especially against many strains of Pseudomonas aeruginosa.

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