7.beta.-Phosphoramido-7.alpha.-methoxycephalosporanic acid deriv

Details 7.beta.-Phosphoramido-7.alpha.-methoxycephalosporanic acid deriv 7.beta.-Phosphoramido-7.alpha.-methoxycephalosporanic acid deriv

1976-07-26

1979-03-20

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, 2602391, C07D50118

Patent

active

041455401

ABSTRACT:
Cephem and penam compounds having a partial structure of formula (II): ##STR1## wherein R.sup.1 and R.sup.2, respectively, represent a hydrocarbon group which is attached to P, either directly or through an oxygen atom, and which may optionally be substituted, and R.sup.3 is a hydrocarbon residue, are useful as intermediates for synthetic penicillins and cephalosporins, which in turn are useful as antibiotics or intermediates for some other synthetic penicillins and cephalosporins having antibiotic activity. To the 6- or 7-amino group of these penam or cephem compounds an objective acyl group can be introduced to give 6- or 7-acyl amino compound in a good yield, without isomerization of 6.alpha.-or 7.alpha.-substituent OR.sup.3 of the penam or cephem compounds.

REFERENCES:
patent: 3978053 (1976-08-01), Hanma et al.
patent: 3980644 (1976-09-01), Lunn
patent: 3987040 (1976-10-01), Cheng et al.
patent: 3997528 (1976-12-01), Yoshioka et al.
patent: 3998817 (1976-12-01), Fukumura et al.
patent: 4043991 (1977-08-01), Hamma et al.
Tetrahedron Letters No. 16, pp. 1307-1310 (1976).
Tetrahedron Letters No. 14, pp. 1307-1310 (1974).

Affiliated with

Also associated with

Rating

7.beta.-Phosphoramido-7.alpha.-methoxycephalosporanic acid deriv does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 7.beta.-Phosphoramido-7.alpha.-methoxycephalosporanic acid deriv, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7.beta.-Phosphoramido-7.alpha.-methoxycephalosporanic acid deriv will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-222087