7.beta.-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and a

Details 7.beta.-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and a 7.beta.-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and a

1975-08-26

1981-03-17

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424246, 544 17, 544 26, 544 27, 544 29, A61K 31545, C07D50159

Patent

active

042567394

ABSTRACT:
7.beta.-Amino-3-R.sub.3 -thio-3-cephem-4-carboxylic acid compounds of the formula ##STR1## wherein R.sub.1.sup.a represents hydrogen or an amino protective group R.sub.1.sup.A and R.sub.1.sup.b represents hydrogen or an acyl group Ac, or R.sub.1.sup.a and R.sub.1.sup.b conjointly represent a divalent amino protective group, R.sub.2 represents hydroxyl or a radical R.sub.2.sup.A which, conjointly with the carbonyl grouping --C(.dbd.O)--, forms a protected carboxyl group and R.sub.3 represents an unsubstituted or substituted hydrocarbon radical or an unsubstituted or substituted heterocyclic radical, and salts of such compounds with salt-forming groups possess antibiotic properties.

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patent: 4123528 (1978-10-01), Cama et al.
patent: 4150156 (1979-04-01), Beattie et al.

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