7'-amino-naphthazarin antibiotic derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...


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548241, 549264, C07D21302, C07D31500




New naphthazarin derivatives obtained by introducing in the 7' position of Purpuromycin or .gamma.-Rubromycin an amino or a monosubstituted amino group.
The compounds of the invention show antibiotic activity against Gram positive and Gram negative microorganisms, fungi and protozoa and are suitable for the treatment of vaginal infections.

patent: 5475010 (1995-12-01), Trani et al.


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