Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-01-17
1998-06-16
Fan, Jane
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D20904
Patent
active
057672830
ABSTRACT:
Novel heterobicyclic sulfonamide and sulfonic ester derivatives represented by the following general formula (I), which exhibit an antitumor activity and are lowly toxic, and processes for the preparation thereof.
A sulfonamide derivative and a sulfonic ester derivative represented by the general formula (I) or a pharmacologically acceptable salt thereof: ##STR1## wherein variables A, W, X, B, C, Y, Z are as defined in the specification.
REFERENCES:
CA 66:85664, Marc et al., 1967
CA 61:13271C, Hiremath et al., 1964.
Paul G. Gassman et al., J. Chem Soc. D., vol. 22, pp. 1437-1438, 1971.
Masanobu Tani et al., Heterocycles, vol. 34, No. 12, pp. 2349-2363, 1992.
Yasuoki Murakami et al., Terahedron Letters, vol. 30, No. 16, pp. 2099-2100, 1989.
S. Siddiqui et al., "Some New Derivatives of Harmaline Series of Bases", Z. Naturfarsch 41B (12), 1583-6, (1986).
Kito Kyosuke
Koyanagi Nozomu
Nagasu Takeshi
Okauchi Tatsuo
Owa Takashi
Eisai Co. Ltd.
Fan Jane
LandOfFree
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