7-(.alpha.-(4 -Hydroxy-1,5-naphthyridine-3-carbonamido)-.alpha.-

Details 7-(.alpha.-(4 -Hydroxy-1,5-naphthyridine-3-carbonamido)-.alpha.- 7-(.alpha.-(4 -Hydroxy-1,5-naphthyridine-3-carbonamido)-.alpha.-

1976-04-05

1977-12-06

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 27, 544 22, A61K 31545, C07D50136

Patent

active

040617483

ABSTRACT:
A cephalosporin derivative of formula (I): ##STR1## wherein X is an --OCOCH.sub.3 group or an -S-Het group in which Het is a 5- or 6-membered heterocyclic ring containing one to four hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur atoms, which may be substituted with one or more substituents, and the non-toxic pharmaceutically acceptable salts thereof which are useful as an antimicrobial material and which are prepared by the reaction of a compound of formula (II): ##STR2## or a reactive derivative thereof, with a compound of formula (III): ##STR3## wherein X is as defined above, or a derivative thereof.

REFERENCES:
patent: 3954802 (1976-05-01), Kocsis et al.

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