7, 8 and 9-substituted tetracycline compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C549S378000

Reexamination Certificate

active

07875649

ABSTRACT:
7, 8 and 9-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7, 8 and 9-substituted tetracycline compounds are described.

REFERENCES:
patent: 2980584 (1961-04-01), Hammer
patent: 2990331 (1961-06-01), Neumann et al.
patent: 3007965 (1961-11-01), Growich
patent: 3062717 (1962-11-01), Hammer
patent: 3165531 (1965-01-01), Blackwood et al.
patent: 3226436 (1965-12-01), Petisi et al.
patent: RE26253 (1967-08-01), Petisi et al.
patent: 3338963 (1967-08-01), Patisi et al.
patent: RE26271 (1967-09-01), Boothe et al.
patent: 3341585 (1967-09-01), Bitha et al.
patent: 3345379 (1967-10-01), Martell et al.
patent: 3345410 (1967-10-01), Winterbottom et al.
patent: 3360561 (1967-12-01), Zambrano
patent: 3373193 (1968-03-01), Alexander et al.
patent: 3397230 (1968-08-01), Winterbottom et al.
patent: 3403179 (1968-09-01), Zambrano
patent: 3454697 (1969-07-01), Joyner et al.
patent: 3483251 (1969-12-01), Zambrano
patent: 3518306 (1970-06-01), Ross et al.
patent: 3557280 (1971-01-01), Weber et al.
patent: 3579579 (1971-05-01), Hlavka et al.
patent: 3609188 (1971-09-01), Esse et al.
patent: 3674859 (1972-07-01), Beutel et al.
patent: 3849493 (1974-11-01), Conover
patent: 3862225 (1975-01-01), Conover et al.
patent: 3901942 (1975-08-01), Bernardi et al.
patent: 3957980 (1976-05-01), Noseworthy
patent: 4018889 (1977-04-01), Armstrong
patent: 4024272 (1977-05-01), Rogalski et al.
patent: 4126680 (1978-11-01), Armstrong
patent: 5248797 (1993-09-01), Sum
patent: 5281628 (1994-01-01), Hlavka et al.
patent: 5284963 (1994-02-01), Sum et al.
patent: 5326759 (1994-07-01), Hlavka et al.
patent: 5328902 (1994-07-01), Sum et al.
patent: 5371076 (1994-12-01), Lee et al.
patent: 5380888 (1995-01-01), Sum et al.
patent: 5386041 (1995-01-01), Sum et al.
patent: 5401729 (1995-03-01), Sum et al.
patent: 5401863 (1995-03-01), Hlavka et al.
patent: 5420272 (1995-05-01), Sum et al.
patent: 5430162 (1995-07-01), Sum et al.
patent: 5442059 (1995-08-01), Sum et al.
patent: 5457096 (1995-10-01), Sum et al.
patent: 5466684 (1995-11-01), Sum et al.
patent: 5494903 (1996-02-01), Hlavka et al.
patent: 5495018 (1996-02-01), Sum et al.
patent: 5495030 (1996-02-01), Sum et al.
patent: 5495031 (1996-02-01), Sum et al.
patent: 5512553 (1996-04-01), Sum et al.
patent: 5529990 (1996-06-01), Hlavka et al.
patent: 5530117 (1996-06-01), Hlavka et al.
patent: 5532227 (1996-07-01), Golub et al.
patent: 5567692 (1996-10-01), Sum et al.
patent: 5639742 (1997-06-01), Lee et al.
patent: 5675030 (1997-10-01), Krishnan et al.
patent: 5789395 (1998-08-01), Amin et al.
patent: 5834450 (1998-11-01), Su
patent: 5886175 (1999-03-01), Sum et al.
patent: 6500812 (2002-12-01), Nelson et al.
patent: 6506740 (2003-01-01), Ashley et al.
patent: 6617318 (2003-09-01), Nelson et al.
patent: 6624168 (2003-09-01), Nelson et al.
patent: 6642270 (2003-11-01), Nelson et al.
patent: 6683068 (2004-01-01), Nelson et al.
patent: 6818634 (2004-11-01), Nelson et al.
patent: 6818635 (2004-11-01), Nelson et al.
patent: 6833365 (2004-12-01), Levy et al.
patent: 6841546 (2005-01-01), Draper et al.
patent: 6846939 (2005-01-01), Nelson et al.
patent: 6849615 (2005-02-01), Nelson et al.
patent: 7001918 (2006-02-01), Huss et al.
patent: 7045507 (2006-05-01), Draper et al.
patent: 7056902 (2006-06-01), Nelson et al.
patent: 7067681 (2006-06-01), Nelson et al.
patent: 7094806 (2006-08-01), Nelson et al.
patent: 7208482 (2007-04-01), Garcia-Luzon et al.
patent: 7521437 (2009-04-01), Nelson et al.
patent: 2002/0128237 (2002-09-01), Nelson et al.
patent: 2002/0160987 (2002-10-01), Ashley et al.
patent: 2003/0195174 (2003-10-01), Ashley et al.
patent: 2004/0002481 (2004-01-01), Ashley et al.
patent: 2004/0024548 (2004-02-01), Genther et al.
patent: 2004/0033966 (2004-02-01), Redkar et al.
patent: 2004/0063674 (2004-04-01), Levy et al.
patent: 2004/0067912 (2004-04-01), Hlavka et al.
patent: 2004/0092490 (2004-05-01), Draper et al.
patent: 2004/0138183 (2004-07-01), Nelson et al.
patent: 2004/0176334 (2004-09-01), Nelson et al.
patent: 2004/0214800 (2004-10-01), Levy et al.
patent: 2004/0214801 (2004-10-01), Nelson et al.
patent: 2004/0242548 (2004-12-01), Draper et al.
patent: 2004/0266740 (2004-12-01), Huss et al.
patent: 2005/0020545 (2005-01-01), Draper et al.
patent: 2005/0026875 (2005-02-01), Nelson et al.
patent: 2005/0026876 (2005-02-01), Nelson et al.
patent: 2005/0038002 (2005-02-01), Nelson et al.
patent: 2005/0070510 (2005-03-01), Draper et al.
patent: 2005/0119235 (2005-06-01), Nelson et al.
patent: 2005/0137174 (2005-06-01), Ohemeng et al.
patent: 2005/0143352 (2005-06-01), Nelson et al.
patent: 2005/0143353 (2005-06-01), Nelson et al.
patent: 2005/0215532 (2005-09-01), Levy et al.
patent: 2005/0245491 (2005-11-01), Hlavka et al.
patent: 2005/0250744 (2005-11-01), Levy et al.
patent: 2005/0267079 (2005-12-01), Hlavka et al.
patent: 2005/0282787 (2005-12-01), Myers et al.
patent: 2005/0288262 (2005-12-01), Bandarage et al.
patent: 2006/0003971 (2006-01-01), Nelson
patent: 2006/0084634 (2006-04-01), Huss et al.
patent: 2006/0089336 (2006-04-01), Nelson et al.
patent: 2006/0148765 (2006-07-01), Nelson et al.
patent: 2006/0166944 (2006-07-01), Berniac et al.
patent: 2006/0166945 (2006-07-01), Abato et al.
patent: 2006/0166946 (2006-07-01), Nelson et al.
patent: 2006/0194773 (2006-08-01), Levy et al.
patent: 2006/0205698 (2006-09-01), Nelson et al.
patent: 2006/0281717 (2006-12-01), Berniac et al.
patent: 2007/0093455 (2007-04-01), Abato et al.
patent: 2008/0070873 (2008-03-01), Alekshun et al.
patent: 2008/0118979 (2008-05-01), Draper et al.
patent: 2008/0287401 (2008-11-01), Johnston et al.
patent: 2008/0312193 (2008-12-01), Assefa et al.
patent: 2009/0118269 (2009-05-01), Berniac et al.
patent: 2009/0156842 (2009-06-01), Seyedi et al.
patent: 0535346 (1993-04-01), None
patent: 0536515 (1993-04-01), None
patent: 0582788 (1994-02-01), None
patent: 0582790 (1994-02-01), None
patent: 0582810 (1994-02-01), None
patent: 0582829 (1994-02-01), None
patent: 0618190 (1994-10-01), None
patent: 951252 (1964-03-01), None
patent: 1469384 (1977-04-01), None
patent: WO-9634852 (1996-11-01), None
patent: WO-9937306 (1999-07-01), None
patent: WO-00/28983 (2000-05-01), None
patent: WO-2005/082860 (2005-02-01), None
Alves, A.B., et al., “Short synthesis of azafluorenone alkaloids using transition metal-catalyzed cross coupling tactics,”Tetrahedron Lett., vol. 29(18):2135-36 (1988).
Berge, S.M., et al., “Pharmaceutical Salts,”J. Pharm.Sci., vol. 66(1):1-19 (1977).
Boothe, J., et al., “6-Deoxytetracyclines. I. Chemical Modification by Electrophilic Substitution,”J. Am. Chem. Soc., vol. 82:1253-4 (1960).
Cheng, W., et al., “Synthetic connections to the aromatic directed metalation reaction. Iterative ortho metalation-cross coupling tactics for the construction of polyphenyls,”Tetrahedron Lett., vol. 28(43):5097-98 (1987).
Koza et al., “Palladium Catalyzed C-N Bond Formation in the Synthesis of 7-Amino-Substituted Tetracyclines”,JOC Note, vol. 67:5025-5027 (2002).
Koza et al., “Synthesis and Biological Evaluation of 9-Substituted Tetracycline Derivatives”,Bio. and Med. Chem. Ltrs., vol. 12:2163-2165 (2002).
Koza, D.J., “Synthesis of 7-substituted tetracycline derivatives,”Organic Lett., vol. 2:815-17 (2000).
Koza, D.J., “The synthesis of 8-substituted tetracycline derivatives, the first 8-position carbon-carbon bond,”Tetrahedron Lett., vol. 41:5017-20 (2000).
Martell, et al., “The 6-deoxytetracyclines. VII. Alkylated aminotetracyclines possessing unique antibacterial activity,”J. Med. Chem., vol. 10(3):359-63 (1967).
Muller, D., et al., “A new strategy for the synthesis of biflavonoids via arylboronic acids,”Tetrahedron Lett., vol. 32(20):2229-32 (1991).
Murahashi, S-I, et al., “Stereoselective synthesis of alkenes and alkenyl sulfides from alkenyl halides using palladium and ruthenium catalyst”J. Org. Chem., vol. 44(14):2408 (1979).
Sharp, M.J., et al., &#x

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